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Copyright (c) 2025 Wasnaa Jomaa Mohammed, Hala Mohammed
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
The undersigned hereby assign all rights, included but not limited to copyright, for this manuscript to CMB Association upon its submission for consideration to publication on Cellular and Molecular Biology. The rights assigned include, but are not limited to, the sole and exclusive rights to license, sell, subsequently assign, derive, distribute, display and reproduce this manuscript, in whole or in part, in any format, electronic or otherwise, including those in existence at the time this agreement was signed. The authors hereby warrant that they have not granted or assigned, and shall not grant or assign, the aforementioned rights to any other person, firm, organization, or other entity. All rights are automatically restored to authors if this manuscript is not accepted for publication.Multi drug resistant Pseudomonas aeruginosa in burn infection among Iraq patients
Corresponding Author(s) : Hala Mohammed
Cellular and Molecular Biology,
Vol. 71 No. 8: Issue 8
Abstract
Pseudomonas aeruginosa is a prominent opportunistic pathogen, especially in burn wound infections, and is often associated with high morbidity and mortality due to its multidrug resistance (MDR) characteristics.This study aimed to evaluate the multidrug resistance profile and perform a molecular phylogenetic analysis of P. aeruginosa isolates recovered from human burn infection sample .Clinical specimens from burn wounds were subjected to traditional culture techniques and biochemical identification to isolate P. aeruginosa. The antibiotic susceptibility patterns were determined using the disc diffusion method according to CLSI guidelines. Molecular identification and phylogenetic characterization were performed using PCR amplification and Sanger sequencing of the 16S rRNA gene.The isolates demonstrated resistance to multiple antibiotics, notably cefixime and meropenem, indicating a multidrug-resistant phenotype. PCR confirmed the presence of P. aeruginosa through successful amplification of the 16S rRNA gene. Sequencing results and phylogenetic analysis revealed a high degree of genetic similarity between the local isolate and P. aeruginosa strains reported globally, suggesting potential international dissemination or conserved evolutionary patterns.
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