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Anti-inflammatory and wound healing effects of an essential oils-based bioadhesive gel after oral mucosa biopsies: preliminary results
Corresponding Author(s) : Elena Maria Varoni
elena.varoni@unimi.it
Cellular and Molecular Biology,
Vol. 64 No. 8: Biosynthesis, metabolism and biological activities of natural products from medicinal and food plants
Abstract
Post-operative management of patients receiving oral biopsy includes the control of edema, pain, infection, and re-epithelization at the surgical site. This clinical study investigates the topical use of a bioadhesive gel, containing essential oils, to promote wound healing and prevent post-operative pain and infection, avoiding the need for surgical suture and chlorhexidine applications. Ten patients, who needed to receive oral biopsies (≤6 mm in diameter) for the diagnosis of mucosal oral lesions, were enrolled. The bioadhesive gel successfully controlled the post-surgical pain; at 1-week follow-up visit, no signs of infection nor side effects were reported and the surgical sites were completely healed. The bioadhesive gel resulted in a very promising agent for the post-operative management of oral biopsy site, without the need for surgical suture and chlorhexidine applications.
Keywords
Bioadhesive gel
Essential oils
Pain
Oral biopsy
Wound healing.
Scotti, F., Decani, S., Sardella, A., Iriti, M., Varoni, E. M., & Lodi, G. (2018). Anti-inflammatory and wound healing effects of an essential oils-based bioadhesive gel after oral mucosa biopsies: preliminary results. Cellular and Molecular Biology, 64(8), 78–83. https://doi.org/10.14715/cmb/2018.64.8.12
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