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Vol. 66 No. 3: Issue 3

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Genetic biomarkers: Potential roles in cancer diagnosis

https://doi.org/10.14715/cmb/2020.66.3.1
Rozhgar A Khailany
Department of Biology, College of Science, University of Salahaddin-Erbil, Iraq
Sherwan Ahmed Aziz
Department of Surgery, Hawler Medical University, Erbil, Iraq
Suhel Mawlood Najjar
Department of Anatomy and Histology, Hawler Medical University, Erbil, Iraq
Muhammad Safdar
Department of Breeding and Genetics, Cholistan University of Veterinary & Animal Sciences, Bahawalpur, Pakistan
Mehmet Ozaslan
Department of Biology, Gaziantep University, Gaziantep, Turkey

Corresponding Author(s) : Rozhgar A Khailany

rozhgar.mohammed@su.edu.krd

Cellular and Molecular Biology, Vol. 66 No. 3: Issue 3

Abstract

Biomarkers are indicators of pathogenic processes, typical biological processes, or pharmacological reactions to a therapy. It has several potential usages in cancer; differential diagnosis, prognosis, risk assessment, therapeutic response, and monitoring of disease progression. Recently, advances in oncomarkers raised significant opportunities for enhancing management of cancer. Chromosomal aberration, molecular impairment and epigenetic alteration might be applied to diagnose and prognose cancer and its epidemiology. Some oncomarkers are specific and highly sensitive for detection. An oncomarker might be used to see how the body reacts to an intervention or a situation. The present study represents a short review about various genetic oncomarkers with diagnostic and prognostic values.

Keywords

Biomarker Cancer Diagnosis Cytogenetic Molecular genetics Epigenetic
Khailany, R. A., Aziz, S. A., Najjar, S. M., Safdar, M., & Ozaslan, M. (2020). Genetic biomarkers: Potential roles in cancer diagnosis. Cellular and Molecular Biology, 66(3), 1–7. https://doi.org/10.14715/cmb/2020.66.3.1
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