Effect of glycosylated hemoglobin protein molecule in treating diabetes

Kuo Qian; Haiying Dong; Jiayi Qian; Jian Gong

doi:10.14715/cmb/2020.66.5.9

Issue

Vol. 66 No. 5: Issue 5

Issue Published : August 6, 2020

The undersigned hereby assign all rights, included but not limited to copyright, for this manuscript to CMB Association upon its submission for consideration to publication on Cellular and Molecular Biology. The rights assigned include, but are not limited to, the sole and exclusive rights to license, sell, subsequently assign, derive, distribute, display and reproduce this manuscript, in whole or in part, in any format, electronic or otherwise, including those in existence at the time this agreement was signed. The authors hereby warrant that they have not granted or assigned, and shall not grant or assign, the aforementioned rights to any other person, firm, organization, or other entity. All rights are automatically restored to authors if this manuscript is not accepted for publication.

Effect of glycosylated hemoglobin protein molecule in treating diabetes

https://doi.org/10.14715/cmb/2020.66.5.9

Kuo Qian

Haiying Dong

Jiayi Qian

Jian Gong

Corresponding Author(s) : Jian Gong

gongjian_0303@163.com

Cellular and Molecular Biology, Vol. 66 No. 5: Issue 5
Article Published : July 31, 2020

Abstract

The object of this study was to observe and analyze the effect of glycosylated hemoglobin in treating diabetes and provide valuable guidance for clinical treatment. For this purpose, 160 patients treated in our hospital who were definitely diagnosed with diabetes after relevant examinations were classified into the study group. 160 cases with healthy physical examinations for the same period were enrolled as a reference group. Fasting blood glucose and glycosylated hemoglobin levels were measured in both groups, and inter-group comparisons were made. The detection results showed that the study group had significantly higher fasting blood glucose and glycosylated hemoglobin levels than the healthy reference group. The difference was statistically significant (p<0.05). Diabetic patients in the study group were also observed. The results showed that patients with complications had significantly higher fasting blood glucose and glycosylated hemoglobin levels than those without complications. Statistical significance existed, p<0.05. For diabetic patients, glycosylated hemoglobin detection is of great significance in profoundly affecting diabetes diagnosis and treatment and providing positive guidance, which means great value for evaluating disease control effects.

Keywords

glycosylated hemoglobin diabetes application effect

Qian, K., Dong, H., Qian, J., & Gong, J. (2020). Effect of glycosylated hemoglobin protein molecule in treating diabetes. Cellular and Molecular Biology, 66(5), 45–48. https://doi.org/10.14715/cmb/2020.66.5.9

Download Citation

References

Xiaoming Q. Observation on the clinical application of glycosylated hemoglobin in the treatment of diabetes. Diabetes New World 2017; 20(4):69-70.
Zhao X. Clinical observation of metformin application in patients with type 2 diabetes. Guide of China Medicine 2016; 14(27): 69-69.
Haitao Shi. Clinical observation of liraglutide in the treatment of type 2 diabetes patients with abdominal obesity. Diabetes New World 2016; 19(3): 32-33, 39.
Guo Yamei, Shang Youquan, Su Wei et al. Application of FPG combined with OGTT 2 h blood glucose and glycosylated hemoglobin in diabetes screening. Hebei Medical Journal 2017; 39(5): 744-745.
Lamos EM, Wijesinha MA, Ramhmdani S, Magder LS, Silver KD. Role of glycemic control on hospital-related outcomes in patients with diabetes mellitus undergoing renal transplantation. Diabetes Metab Syndr Obes 2017; 10:13.
Bocquet V. Comment on "An algorithm for identification and classification of individuals with type 1 and type 2 diabetes mellitus in a large primary care database”, written by Sharma et al. Clin Epidemiol 2017; 9(24):190-194.
Eknithiset R, Somrongthong R. Effectiveness of a diabetes mellitus pictorial diary handbook program for middle-aged and elderly type 2 diabetes mellitus patients: a quasi-experimental study at Taladnoi Primary Care Unit, Saraburi, Thailand. J Multidiscip Healthc 2017; 5(10):563-569.
Min Z, Lixia F. Clinical significance of glycosylated hemoglobin in the diagnosis of diabetes. Psychological doctor 2017; 23(31): 86-87.
Lei Z. Clinical significance of glycosylated hemoglobin in the detection of diabetes. Diabetes New World 2017; 20 (11): 69-70.
Alzaheb R, Altemani A. The prevalence and determinants of poor glycemic control among adults with type 2 diabetes mellitus in Saudi Arabia. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2018; 2(9):325-329.
Jaworski M, Panczyk M, Cedro M, Kucharska A. Adherence to dietary recommendations in diabetes mellitus: disease acceptance as a potential mediator. Patient Prefer Adherence 2018; 9(3):670-675.
Fuying L, Guocai G, Dunzhen L. Clinical value of glycosylated hemoglobin in the diagnosis treatment and risk of complications forecast. Int J Lab Med 2015; (11): 1591-1592.
Guo G, Fu M, Wei S, Chen R. Impact of diabetes mellitus on the risk and survival of nasopharyngeal carcinoma: a meta-analysis. OncoTargets Ther 2018; 11:1193.
Ghaheri M, Miraghaei S, Babaei A, Mohammadi B, Kahrizi D, Minoosh, Z, Haghighi S, Bahrami G. Effect of Stevia rebaudiana Bertoni extract on sexual dysfunction in Streptozotocin-induced diabetic male rats. Cell Mol Biol, 2018; 64(2): 6-10.
Bordbar M, Darvishzadeh R, Pazhouhandeh M, Kahrizi D. An overview of genome editing methods based on endonucleases. Modern Genetics J 2020; 15(2): 75-92.

References

Xiaoming Q. Observation on the clinical application of glycosylated hemoglobin in the treatment of diabetes. Diabetes New World 2017; 20(4):69-70.

Zhao X. Clinical observation of metformin application in patients with type 2 diabetes. Guide of China Medicine 2016; 14(27): 69-69.

Haitao Shi. Clinical observation of liraglutide in the treatment of type 2 diabetes patients with abdominal obesity. Diabetes New World 2016; 19(3): 32-33, 39.

Guo Yamei, Shang Youquan, Su Wei et al. Application of FPG combined with OGTT 2 h blood glucose and glycosylated hemoglobin in diabetes screening. Hebei Medical Journal 2017; 39(5): 744-745.

Lamos EM, Wijesinha MA, Ramhmdani S, Magder LS, Silver KD. Role of glycemic control on hospital-related outcomes in patients with diabetes mellitus undergoing renal transplantation. Diabetes Metab Syndr Obes 2017; 10:13.

Bocquet V. Comment on "An algorithm for identification and classification of individuals with type 1 and type 2 diabetes mellitus in a large primary care database”, written by Sharma et al. Clin Epidemiol 2017; 9(24):190-194.

Eknithiset R, Somrongthong R. Effectiveness of a diabetes mellitus pictorial diary handbook program for middle-aged and elderly type 2 diabetes mellitus patients: a quasi-experimental study at Taladnoi Primary Care Unit, Saraburi, Thailand. J Multidiscip Healthc 2017; 5(10):563-569.

Min Z, Lixia F. Clinical significance of glycosylated hemoglobin in the diagnosis of diabetes. Psychological doctor 2017; 23(31): 86-87.

Lei Z. Clinical significance of glycosylated hemoglobin in the detection of diabetes. Diabetes New World 2017; 20 (11): 69-70.

Alzaheb R, Altemani A. The prevalence and determinants of poor glycemic control among adults with type 2 diabetes mellitus in Saudi Arabia. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy 2018; 2(9):325-329.

Jaworski M, Panczyk M, Cedro M, Kucharska A. Adherence to dietary recommendations in diabetes mellitus: disease acceptance as a potential mediator. Patient Prefer Adherence 2018; 9(3):670-675.

Fuying L, Guocai G, Dunzhen L. Clinical value of glycosylated hemoglobin in the diagnosis treatment and risk of complications forecast. Int J Lab Med 2015; (11): 1591-1592.

Guo G, Fu M, Wei S, Chen R. Impact of diabetes mellitus on the risk and survival of nasopharyngeal carcinoma: a meta-analysis. OncoTargets Ther 2018; 11:1193.

Ghaheri M, Miraghaei S, Babaei A, Mohammadi B, Kahrizi D, Minoosh, Z, Haghighi S, Bahrami G. Effect of Stevia rebaudiana Bertoni extract on sexual dysfunction in Streptozotocin-induced diabetic male rats. Cell Mol Biol, 2018; 64(2): 6-10.

Bordbar M, Darvishzadeh R, Pazhouhandeh M, Kahrizi D. An overview of genome editing methods based on endonucleases. Modern Genetics J 2020; 15(2): 75-92.

Author biographies is not available.