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Bio-therapeutics effects of probiotic strain on the gastrointestinal health of severely acute malnourished children
Corresponding Author(s) : Habib-Ur- Rehman
javad.sharifirad@gmail.com
Cellular and Molecular Biology,
Vol. 66 No. 4: Medicinal plants and natural products
Abstract
The core objective was to evaluate the effect of probiotic fortification at three phases of formula milk administration in malnourished children. A dose related effect was determined in 30 severely acute malnourished children (6-59 months) in a double-blind, randomized design. According to the results, serum albumin levels, treatment T2 (6 billion cfu) has significantly increased albumin levels (3.7g/dL) and the effect of phase-III (Plumpy'nut) was found to be better. Results regarding sodium levels showing probiotic-dose have significant effect (P≤0.05) in phases as well. Moreover, the effect of T1 i.e. 3 billion cfu of probiotics has significantly reduced sodium levels (141.8mmol/L) vs. others and the effect of phase-II was better on reducing sodium levels. which is further confirmed in terms of reduced erythrocyte sedimentation rate levels at phase-III (29.566 vs. phase-II, 41.3 and phase-I, 46.533 mm/h). Conclusively, the effect of 6 billion cfu at phase-III was more effective on blood parameters.
Keywords
Probiotics
Hematological parameters
Serum enzymes
Malnutrition.
Rehman, H.-U.-., Nasir, M., Abdul Jabbar, M., Ayaz, M., Ali, M. A., Imran, M., Gondal, T. A., Tufail, T., Aslam, F., Qaisrani, T. B., Sattar, M. U., Salehi, B., Martins, N., & Sharifi-Rad, J. (2020). Bio-therapeutics effects of probiotic strain on the gastrointestinal health of severely acute malnourished children. Cellular and Molecular Biology, 66(4), 65–72. https://doi.org/10.14715/cmb/2020.66.4.11
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