Ibrahim  Jafri

doi:10.14715/cmb/2023.69.8.16

Issue

Vol. 69 No. 8: Issue 8

Issue Published : September 15, 2023

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MiRNA a New Insight in Metabolic and Human Diseases: A Review

A New Insight into the Roles of MiRNAs

https://doi.org/10.14715/cmb/2023.69.8.16

Ibrahim Jafri

Department of Biotechnology, College of Sciences, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia

Corresponding Author(s) : Ibrahim Jafri

i.jafri@tu.edu.sa

Cellular and Molecular Biology, Vol. 69 No. 8: Issue 8
Article Published : August 31, 2023

Abstract

The purpose of this research is to examine existing studies on the association between microRNAs (miRNA) and age-related disorders. The miRNAs are small, noncoding RNA molecules with the ability to regulate gene expression. These are well-established in extracellular circulation, including various types of diseases such as cancer, cardiovascular diseases, and diabetes. Similarly, several miRNAs are associated with certain age-related conditions, such as increased miR-21 expression in cancer patients. Besides that, the miR-122 in atherosclerosis patients played an essential role in gene expression and disease. Therefore, the miRNA has the potential to serve as a reliable biomarker for the early detection, monitoring of progression, and regression of age-related diseases. To have a complete understanding of the mechanisms and the direct long-term effects that the miRNA has on the pathophysiology and development of diseases, additional research is required.

Keywords

MicroRNA; MicroRNA Expression; Aging, age-related diseases; Biomarker.

Jafri, I. . (2023). MiRNA a New Insight in Metabolic and Human Diseases: A Review : A New Insight into the Roles of MiRNAs. Cellular and Molecular Biology, 69(8), 102–110. https://doi.org/10.14715/cmb/2023.69.8.16