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Copyright (c) 2025 Salah Qadir Mahmood, Bakhtyar Kamal Talabany Talabany, Taib Ahmed Hama Soor
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The undersigned hereby assign all rights, included but not limited to copyright, for this manuscript to CMB Association upon its submission for consideration to publication on Cellular and Molecular Biology. The rights assigned include, but are not limited to, the sole and exclusive rights to license, sell, subsequently assign, derive, distribute, display and reproduce this manuscript, in whole or in part, in any format, electronic or otherwise, including those in existence at the time this agreement was signed. The authors hereby warrant that they have not granted or assigned, and shall not grant or assign, the aforementioned rights to any other person, firm, organization, or other entity. All rights are automatically restored to authors if this manuscript is not accepted for publication.Molecular and cellular effects of chronic low-dose X-ray exposure on thyroid function and blood cell parameters in radiology staff
Corresponding Author(s) : Salah Qadir Mahmood
Cellular and Molecular Biology,
Vol. 71 No. 6: Issue 6
Abstract
This study investigated the impact of long-term, low-dose occupational exposure to X-rays on thyroid function and hematological parameters in radiology staff. A cross-sectional analysis was conducted on 136 radiology and radiation-related employees. Thyroid status, assessed via ultrasonography and serum T3, T4, and TSH measurements, was compared with complete blood counts (CBC). While no significant gender-based differences in thyroid hormones or structure were observed, TSH levels correlated significantly with occupational group (P=0.016), and T3 levels correlated with working hours (P=0.03). Radiologists exhibited higher RDW-CV compared to radiographers and other staff (P=0.009). Significant gender differences were noted in lymphocyte counts, hemoglobin, red blood cells, and hematocrit. In males, WBC and MCHC fluctuated significantly with increased working hours. These findings suggest that chronic, low-dose X-ray exposure may influence thyroid hormone regulation and hematopoiesis in radiology professionals. Further research is warranted to elucidate the underlying cellular and molecular mechanisms and to refine radiation safety protocols.
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