Isolation, identification and characterization of Morganella morganii from Naja naja atra in Beijing, China

H-F. Wang; L-Y. Du; J. Luo; H-X. He

doi:10.14715/cmb/2017.63.7.9

Issue

Vol. 63 No. 7: Issue 7

Issue Published : August 22, 2017

The undersigned hereby assign all rights, included but not limited to copyright, for this manuscript to CMB Association upon its submission for consideration to publication on Cellular and Molecular Biology. The rights assigned include, but are not limited to, the sole and exclusive rights to license, sell, subsequently assign, derive, distribute, display and reproduce this manuscript, in whole or in part, in any format, electronic or otherwise, including those in existence at the time this agreement was signed. The authors hereby warrant that they have not granted or assigned, and shall not grant or assign, the aforementioned rights to any other person, firm, organization, or other entity. All rights are automatically restored to authors if this manuscript is not accepted for publication.

Isolation, identification and characterization of Morganella morganii from Naja naja atra in Beijing, China

https://doi.org/10.14715/cmb/2017.63.7.9

H-F. Wang

Department of Environmental and Chemical Engineering, Yellow River Conservancy Technical Institute, Dong Jing Avenue, Kaifeng, People's Republic of China

L-Y. Du

National Research Center for Wildlife-Borne Diseases, Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beichen West Road, Chaoyang District, Beijing, People's Republic of China

J. Luo

H-X. He

Corresponding Author(s) : H-X. He

hehx@ioz.ac.cn

Cellular and Molecular Biology, Vol. 63 No. 7: Issue 7
Article Published : August 15, 2017

Abstract

Morganella morganii is an important opportunistic human pathogen and belongs to the family of Enterobacteriaceae. Although it is widely distribution, it only be considered a rare cause of human infections. We report the isolate of M. morganii from Naja naja atra following infections of heart, lung and liver. Seven strains were confirmed using 16S rDNA amplified and sequences. Antimicrobial susceptibility testing of M. morganii isolates demonstrated ubiquitous resistance to ampicillin, amoxicillin/clavulanic acid, cefazolin, cephalothin, sulfamethoxazole/trimethoprim, sulfamethoxazole et al. However, M. morganii ubiquitous susceptible to piperacillin, ampicillin/sulbactam, piperacillin/tazobactam, cefixime et al. Further investigate display gyr B and Sul2 genes presence in all M. morganii isolates. AAC(3)-II was found in E2, E3 and E6 M. morganii. gyrA and qnrB expression in M3 and M6 M. morganii. This is the first description in M. morganii carrying AAC(3)-II, gyrB, gyrA, qnrB, and Sul2 genes from Naja naja atra, which suggests the increasing risk of pathogen transmission between humans and wildlife.

Keywords

Antibiotics Resistance genes Morganella Morganii Naja naja atra.

Wang, H.-F., Du, L.-Y., Luo, J., & He, H.-X. (2017). Isolation, identification and characterization of Morganella morganii from Naja naja atra in Beijing, China. Cellular and Molecular Biology, 63(7), 52–58. https://doi.org/10.14715/cmb/2017.63.7.9