Published: December 28, 2025

Original Research Articles

Modulatory effects of Mentha longifolia and Mentha spicata essential oils on Candida albicans biofilm formation

Mentha oils affect Candida albicans

1-9
Ayshah Alrashidi, Badria Abd El-Rahman Husin Husin, Meshari Alazmi, Safa Mustafa Ibrahim, Abdel Moneim E. Sulieman

Piezo1-mediated cellular apoptosis in breast cancer cells triggered by ultrasound and microbubbles

Piezo1 regulates apoptosis

10-15
Nina Qu, Menglu Bi, Qingkai Meng, Hexiu Liu, Jingbo Wang, Xiaoli Cao

Whole-grain millets attenuate atherosclerosis by modulating cholesterol metabolism and the FGF-2/PI3K/Akt and Wnt-1/β-catenin pathways in high-cholesterol-fed rats

Cardioprotection of millets via FGF-2 and Wnt/ꞵ catenin signaling

22-30
Haritha Rajan, Abhirami Sunitha, Mani Sebastian, Amrutha Dileep Kumar Sreeja Kumari, Salu Valsala Sasi Kumar, Helen Antony

Structure-based identification of liensinine as a natural allosteric SHP2 inhibitor with anti-proliferative activity in HepG2 cells

Liensinine as a natural SHP2 inhibitor

31-38
Beom Su Seo, Dong Oh Moon

Characterization of COVID-19 patients in clinical, epidemiological, and laboratory settings: the role of vitamin D binding protein and vitamin D level in severity

Serum vitamin D and DBP in COVID-19 patients

39-48
Aleen Sardar Al-Noori, Ahmed Mohamed Salih, Muayad Aghali Merza

Curcumin-mediated synthesis of copper-doped TiO2 nanocomposite for potentially promising antioxidant, wound healing, and anti-apoptosis

Curcumin-synthesized Cu-TiO_2 for biomedicine

49-58
Saja Zubair Dhabian, Mustafa Taher Hatem

Inhibition of the RIPK1-driven necroptotic pathway protects against hypotensive and tachycardic responses to LPS in a rat model of septic shock

Protective effects of Nec-1s against septic shock

59-71
Bahar Tunctan, Sefika Pinar Senol, Dilsah Ezgi Yilmaz, Omer Bahceli, Tuba Kara, Muhammed Ahmed-Reda Elosman

Multidimensional assessment of natural ligands fisetin, morin and rutin against factor XIIa activity using in vitro and in silico studies

Fisetin inhibits coagulation factor XIIa activity

72-80
Hassan A. Madkhali

The role of an immunohistochemical panel including CD45, CK5/6, and ER in classifying challenging breast lesions in Iraqi pathology

CD45, CK5/6 and ER in challenging breast lesions

94-100
Saman Rafeeq Abdullah

TMAO converts cytochrome c into a pro-apoptotic peroxidase by destabilizing the heme-Met80 ligation

TMAO unlocks the apoptotic activity of cytochrome c

110-117
Kuldeep Singh, Anju Kumari, Seemasundari Yumlembam, Nelson Mutum, Radhika Bakhshi, Prachi Rani, Kajal Mavi, Akshita Gupta, Laishram Rajendrakumar Singh

Activation of the Na/K-ATPase oxidant amplification loop by uremic toxins drives adipocyte dysfunction in vitro

Uremic toxins trigger Na/K-ATPase oxidant signaling

118-125
Hari Vishal Lakhani, Muhammad A. Chaudhry, Tilak Khanal, D. Blaine Nease, Joseph I. Shapiro, Komal Sodhi

Structural dynamics of PCSK9 loss-of-function variants: implications for LDL cholesterol regulation and cardiovascular risk

PCSK9 mutations: structure to heart risk

126-138
Mohammed Tarique, Ayyub Ali Patel, Ayaz Khurram Mallick, Rania A. Hussien, Tarek Mahmoud Mirdad, Zia-Ul -Sabah, Rasha Mirdad, Imad Mohammad Alghawanmeh, Mohamed Babiker Abdelrouf Awadelkarim, Mohammad Azhar Kamal, Hani Alothaid

Reviews

Toll-like receptor 3 in hepatitis B and C: a determinant of infection

TLR3 and viral hepatitis B and C

81-93
Abdoul Karim Ouattara, Issoufou Tao, Julien Dembélé, Jacques Simpore

Chronic inflammation in the development of colorectal cancer: pathological model and therapeutic targets

Inflammation-driven colorectal carcinogenesis

101-109
Alexander Blagov, Nikolay Shakhpazyan, Olga Maltseva, Elizaveta Korchagina, Alexander Orekhov

Mini Reviews

A systematic review of the toxicity of salsolinol and its metabolites

Toxicity of salsolinol and metabolites

16-21
Jasmine Kaur Sidhu, Hong Yu Wong, Beek Yoke Chin, Kenny Gah Leong Voon, Shamala Salvamani, Anna Pick Kiong Ling, Soi Moi Chye, Rhun Yian Koh