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                    Herbal remedies as alternative to conventional therapies for the treatment of pediatric infectious diseases
Corresponding Author(s) : Javad Sharifi-Rad
 javad.sharifirad@gmail.com 
                        
                    Cellular and Molecular Biology,
                    Vol. 66 No. 4: Medicinal plants and natural products
                    
                    
                  
Abstract
                              Pediatric infections still represent a leading cause of mortality in many developing countries. Since ancient times, traditional healing systems provided some herbal remedies to treat pediatric diseases, only in some cases validated by an evidence-based approach. Therefore, this review covers the herbal remedies in Iranian traditional medicine and aims to assess the potential of phytotherapeutics as safe and effective alternatives to conventional therapies for the treatment of pediatric infectious diseases. Notably, pediatric patients may also benefit from adjuvant therapy, i.e., combined treatment with herbal remedies and conventional therapies, to improve the efficacy of conventional drugs, decrease their adverse effects at the cell-tissue-organ-organism level and reduce the occurrence of microbial strains resistant to antibiotics. Therefore, traditional healing systems still represent an unlimited source of active ingredients to be tested in preclinical assays as well as in humans in terms of efficacy and safety.
                            
                          Keywords
                                                              Traditional healing systems
                                                              Iranian traditional medicine
                                                              Antibiotic resistance
                                                              Phytochemicals
                                                              Phytotherapeutics
                                                              Pediatric
                                                              Infectious diseases.
                                                          
                          Salehi, B., Heravi, R. E., Eydian, Z., Stojanovic-Radic, Z., Martorell, M., Iriti, M., & Sharifi-Rad, J. (2020). Herbal remedies as alternative to conventional therapies for the treatment of pediatric infectious diseases. Cellular and Molecular Biology, 66(4), 45–53. https://doi.org/10.14715/cmb/2020.66.4.8
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