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Copyright (c) 2022 Sulaiman A. Alsalamah , Mohamed Algonuim , Nosiba S, Basher , Sepehr Kahrizi, Abdel Moneim E. Sulieman
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
The undersigned hereby assign all rights, included but not limited to copyright, for this manuscript to CMB Association upon its submission for consideration to publication on Cellular and Molecular Biology. The rights assigned include, but are not limited to, the sole and exclusive rights to license, sell, subsequently assign, derive, distribute, display and reproduce this manuscript, in whole or in part, in any format, electronic or otherwise, including those in existence at the time this agreement was signed. The authors hereby warrant that they have not granted or assigned, and shall not grant or assign, the aforementioned rights to any other person, firm, organization, or other entity. All rights are automatically restored to authors if this manuscript is not accepted for publication.Assessment of The Antibacterial Susceptibility of Ocimum basilicum
Corresponding Author(s) : Abdel Moneim E. Sulieman
Cellular and Molecular Biology,
Vol. 68 No. 8: Issue 8
Abstract
The current study was designed to assess the antibacterial activities of an ethanol extract of Ocimum basilicum (O. basilicum). Using disc diffusion and direct contact methods, the extracts were tested in vitro against three bacterial strains. The direct contact test was used and compared with the agar diffusion test. The optical density was measured using a spectrophotometer to collect data. The results showed that methanol extracts of plant parts of O. basilcum leaves contained tannins, flavonoids, glycosides, and steroids, whereas alkaloids, saponins, and terpenoids. In contrast, O. basilcum seeds contained saponins, flavonoids, and steroids. The O. basilicum stems contained saponins and flavonoids, O. basilucum had antibacterial activity against the identified bacteria. The plant extracts inhibited Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli (E. coli). The result revealed that the Ocimum basilicum leaves were more potent than seeds and stems. Ocimum basilicum ethanol extract combined with established conventional antibiotics may enhance their antimicrobial properties, giving rise to synergistic effects against clinically important bacterial species.
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