Body girdle reduced fat deposition and altered other body parameters in rats

T-R. Li; B-C. Chen; Y-F. Zou; J. Zhang; W. Zhang; B. Dong; X. Li; X-F. Chen

doi:10.14715/cmb/2016.62.12.18

Issue

Vol. 62 No. 12: Issue 12

Issue Published : November 26, 2016

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Body girdle reduced fat deposition and altered other body parameters in rats

https://doi.org/10.14715/cmb/2016.62.12.18

T-R. Li

Department of Intervention and Vascular Surgery, Peking University Third Hospital, Beijing, China

B-C. Chen

Department of Dermatology, Peking University Shenzhen Hospital, Shenzhen, China

Y-F. Zou

Department of Dermatology, Peking University Shenzhen Hospital, Shenzhen, China

J. Zhang

Department of Dermatology, Peking University Shenzhen Hospital, Shenzhen, China

W. Zhang

Biomedical Research Institute, Shenzhen Peking University-the Hong Kong University of Science and Technology Medical Center, Shenzhen, China

B. Dong

National Key Laboratory of Animal Nutrition, China Agricultural University, Beijing, China

X. Li

Department of Intervention and Vascular Surgery, Peking University Third Hospital, Beijing, China

X-F. Chen

Biomedical Research Institute, Shenzhen Peking University-the Hong Kong University of Science and Technology Medical Center, Shenzhen, China

Corresponding Author(s) : X-F. Chen

littlecanva@163.com

Cellular and Molecular Biology, Vol. 62 No. 12: Issue 12
Article Published : October 31, 2015

Abstract

Many women favor in wearing foundation garments to shape their body and show satisfactory figures. However, few investigations have been conducted on the physiological impact of wearing tight garments on the body. In this study, we used girdled rats that were fed with a high fat diet to investigate their physiological condition including alterations in food intake, body weight, fat deposition, and hormone concentrations. Over the experiment period, girdled rats maintained normal plasma and liver cholesterol and triglyceride. Leptin level in girdled rats was significantly lower than that in normal control. The fat tissue of girdled rats was more active in secretion of leptin, which might be mediated by mTOR signaling. Girdled rats showed no difference in hematology analysis during the experiment period. This study showed that a body girdle can significantly reduce fat deposition and alter other body parameters in rats.

Keywords

Fat deposition girdle bound leptin mTOR rat.

Li, T.-R., Chen, B.-C., Zou, Y.-F., Zhang, J., Zhang, W., Dong, B., Li, X., & Chen, X.-F. (2015). Body girdle reduced fat deposition and altered other body parameters in rats. Cellular and Molecular Biology, 62(12), 102–108. https://doi.org/10.14715/cmb/2016.62.12.18