p-Cymene metallo-derivatives: An overview on anticancer activity

Shardar Mohammad Hafiz Hassan; Pranta Ray; Rajib Hossain; Muhammad Torequl Islam; Bahare Salehi; Natália Martins; Javad Sharifi-Rad; Ryszard Amarowicz

doi:10.14715/cmb/2020.66.4.5

Issue

Vol. 66 No. 4: Medicinal plants and natural products

Issue Published : June 23, 2020

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p-Cymene metallo-derivatives: An overview on anticancer activity

https://doi.org/10.14715/cmb/2020.66.4.5

Shardar Mohammad Hafiz Hassan

Department of Pharmacy, Life Science Faculty, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj-8100, Bangladesh

Pranta Ray

Department of Pharmacy, Life Science Faculty, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj-8100, Bangladesh

Rajib Hossain

Department of Pharmacy, Life Science Faculty, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj-8100, Bangladesh

Muhammad Torequl Islam

Department of Pharmacy, Life Science Faculty, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj-8100, Bangladesh

Bahare Salehi

Student Research Committee, School of Medicine, Bam University of Medical Sciences, Bam, Iran

Natália Martins

Faculty of Medicine, University of Porto, Alameda Prof. Herní¢ni Monteiro, 4200-319 Porto, Portugal

Javad Sharifi-Rad

Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, 1991953381 Tehran, Iran

Ryszard Amarowicz

Department of Chemical and Physical Properties of Food, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Tuwima Street 10, 10-748 Olsztyn, Poland

Corresponding Author(s) : Bahare Salehi

bahar.salehi007@gmail.com

Cellular and Molecular Biology, Vol. 66 No. 4: Medicinal plants and natural products
Article Published : June 25, 2020

Abstract

Metallo-drugs have gained a huge attention among scientific community in the couple years. These drugs types have become important compounds in cancer therapy, where, for instance, platinum complexes are being used against many tumors worldwide. Nonetheless, to p-cymene metallo-derivatives a promising anticancer potential has also been increasingly proposed. In this sense, the present review aims to provide an in-depth revision of p-cymene metallo-drugs possible mechanisms of anticancer action for upcoming pharmaceutical and biotechnological prospects. p-cymene metallo-derivatives have revealed very interesting anticancer activities in various test systems, including cancer cells, being thus worth of note to deepen knowledge through clinical trials on their upcoming use for cancer chemotherapy combination.

Keywords

Cancer p-cymene Essential oil Metallo-drugs Chemotherapy Combination therapy.

Hassan, S. M. H., Ray, P., Hossain, R., Islam, M. T., Salehi, B., Martins, N., Sharifi-Rad, J., & Amarowicz, R. (2020). p-Cymene metallo-derivatives: An overview on anticancer activity. Cellular and Molecular Biology, 66(4), 28–32. https://doi.org/10.14715/cmb/2020.66.4.5